For a full list of publications by Jacques Neefjes follow this link to PubMed

 

Selected Publications

Paul, P., van den Hoorn, T., Jongsma, M.L., Bakker, M.J., Hengeveld, R., Janssen, L., Cresswell, P., Egan, D.A., van Ham, M., Ten Brinke, A., Ovaa, H., Beijersbergen, R.L., Kuijl, C., Neefjes, J. A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation. Cell 145, 268-283. [ABSTRACT]

Rocha,N., Kuijl,C., van der Kant,R., Janssen,L., Houben,D., Janssen,H., Zwart,W., and Neefjes,J. (2009). Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning. J. Cell Biol. 185, 1209-1225. [ABSTRACT]

Kuijl,C., Savage,N.D., Marsman,M., Tuin,A.W., Janssen,L., Egan,D.A., Ketema,M., van den Nieuwendijk,R., van den Eeden,S.J., Geluk,A., Poot,A., van der Marel,G., Beijersbergen,R.L., Overkleeft,H., Ottenhoff,T.H., and Neefjes,J. (2007). Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1. Nature 450, 725-730. [ABSTRACT]

Reits,E.A., Hodge,J.W., Herberts,C.A., Groothuis,T.A., Chakraborty,M., Wansley,E.K., Camphausen,K., Luiten,R.M., de Ru,A.H., Neijssen,J., Griekspoor,A., Mesman,E., Verreck,F.A., Spits,H., Schlom,J., van Veelen,P., and Neefjes,J.J. (2006). Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. J Exp Med 203, 1259-1271. [ABSTRACT]

Dantuma,N.P., Groothuis,T.A., Salomons,F.A., and Neefjes,J. (2006). A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling. J Cell Biol 173, 19-26. [ABSTRACT]

Neijssen,J., Herberts,C., Drijfhout,J.W., Reits,E., Janssen,L., and Neefjes,J. (2005). Cross-presentation by intercellular peptide transfer through gap junctions. Nature 434, 83-88. [ABSTRACT]

Michalides,R., Griekspoor,A., Balkenende,A., Verwoerd,D., Janssen,L., Jalink,K., Floore,A., Velds,A., van't Veer,L., and Neefjes,J. (2004). Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer. Cancer Cell 5, 597-605. [ABSTRACT]

Reits,E., Griekspoor,A., Neijssen,J., Groothuis,T., Jalink,K., van Veelen,P., Janssen,H., Calafat,J., Drijfhout,J.W., and Neefjes,J. (2003). Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I. Immunity 18, 97-108. [ABSTRACT]

Reits,E.A. and Neefjes,J.J. (2001). From fixed to FRAP: measuring protein mobility and activity in living cells. Nat. Cell Biol. 3, E145-E147. [ABSTRACT]

Reits,E.A., Vos,J.C., Gromme,M., and Neefjes,J. (2000). The major substrates for TAP in vivo are derived from newly synthesized proteins. Nature 404, 774-778. [ABSTRACT]